DelveInsight’s Achondroplasia Market Insights, Epidemiology, and Market Forecast-2030″ report delivers an in-depth understanding of the Achondroplasia, historical and forecasted epidemiology as well as the Achondroplasia market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.
Achondroplasia Overview
Achondroplasia is the most common of skeletal dysplasia that results in marked short stature (dwarfism). It is a human bone genetic disorder of the growth plate and is the most common form of inherited disproportionate short stature.
Request free sample copy @ https://www.delveinsight.com/sample-request/achondroplasia-market
Regions Covered
List of Key Players involved in the report
Achondroplasia Market Report
The children affected by Achondroplasia are delayed in reaching gross motor milestones such as head control, and independent sitting and walking. There are some serious neurological problems that may also occur due to narrowing of the spinal canal and nerve compression.
Achondroplasia Market Insights
It is caused by one of two mutations (G1138A and G1138C) in the FGFR3 (Fibroblast Growth Factor Receptor 3) gene at chromosome locus 4p16.3. The mutations cause the FGFR3 protein to be overly active, which interferes with skeletal development and leads to disturbances in bone growth seen with this disorder.
Achondroplasia Market Outlook
There is currently no treatment that can cure Achondroplasia since most cases result from unexpected new mutations. Treatment aimed at correcting growth has been tried; however, growth hormone therapy has no significant effect on adult stature.
Achondroplasia Therapies
The only available therapeutic option for Achondroplasia is limb lengthening, an extremely invasive surgical procedure that addresses height but no other Achondroplasia-associated complications. It is very important to check for bone abnormalities, especially in the back. Sometimes, surgery is also needed to correct specific skeletal deformities in patients with severe knock-knee, Kyphosis, or bowed legs. For significant spinal kyphosis, a spinal fusion sometimes is also performed (permanently connecting otherwise separate vertebrae).
Achondroplasia Treatment Market
The current market is occupied with this symptomatic treatment and surgery only. To be effective, a new treatment approach must consider Achondroplasia is a complex disease, correcting the short stature and preventing complications. Understanding the pathophysiology of the disease is essential to achieve this and correcting the growth of all bones affected by the disease, will define the future treatment strategy.
Achondroplasia Pathogenesis
The molecular pathogenesis of Achondroplasia began to unravel with the identification of mutations in transmembrane receptor Fibroblast Growth Factor Receptor 3 (FGFR3). Currently, several approaches are designed to target FGFR3 within the cartilage either by blocking its activation, inhibiting downstream signaling, or increasing its turnover.
Achondroplasia Market Report Scope
Read Detailed Table of Content
1. Key Insights
2. Executive Summary of Achondroplasia
3. Competitive Intelligence Analysis for Achondroplasia
4. Achondroplasia: Market Overview at a Glance
5. Achondroplasia: Disease Background and Overview
6. Patient Journey
7. Achondroplasia Epidemiology and Patient Population
8. Treatment Algorithm, Current Treatment, and Medical Practices
9. Unmet Needs
10. Key Endpoints of Achondroplasia Treatment
11. Marketed Products
12. Emerging Therapies
13. Achondroplasia: Seven Major Market Analysis
14. Attribute analysis
15. 7MM: Market Outlook
16. Access and Reimbursement Overview of Achondroplasia
17. KOL Views
18. Market Drivers
19. Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer
23. About DelveInsight
Achondroplasia Market Report Highlights
Why should you buy this report?
About Us
DelveInsight is a Business Consulting and Market research company, providing expert business solutions for the life science vertical and offering quintessential advisory services in the areas of R&D, Strategy Formulation, Operations, Competitive Intelligence, Competitive Landscaping, and Mergers & Acquisitions.
Media ContactCompany Name: DelveInsight Business Research LLPContact Person: Yash BhardwajEmail: Send EmailPhone: +919650213330Address:304 S. Jones Blvd #2432 City: Las VegasState: NVCountry: United StatesWebsite: https://www.delveinsight.com/